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Systems Biology symposium announcement PDF Print E-mail
Written by Virginia Gonzalez   
Wednesday, 18 March 2009 13:11

Systems Biology symposium announcement


Systems Biology: Integrative, Comparative, and Multi-Scale Modeling
June 11-14, 2009
The 18th Annual Growth Factor and Signal Transduction Conference

PROGRAM:  Systems Biology is an exciting, emerging discipline at the interface of biological and informational sciences. Over the past several decades, biologists have been accumulating detailed knowledge of the building blocks of biological systems e.g., DNA, RNA, genes, proteins, cells, tissues, organs, organisms, and ecologies. Genomics has provided us with an enormous collection of molecular parts. Anatomical, physiological, molecular, cellular, and structural approaches to biology have begun to transform our understanding of how these specific parts of living things function. However, biological systems are more than simply a collection of molecules, cells, or organs. We need to understand how these parts work together to form dynamic functional units so that we can precisely describe, model, and simulate biological systems.

During this Symposium on modeling in Systems Biology, some of the worlds leading experimental and computational scientists and engineers working in microbial, plant, animal, and human systems will convene on the campus of Iowa State University. Shown below are the speakers who have committed to present their recent discoveries as well as discuss current and future research and educational challenges in bioinformatics.  As in past years, the Symposium will be set in a venue designed to promote informal discussion and interaction, potentiating collaborations. It will provide the opportunity for students and younger researchers to gain a working knowledge of the current state of the field and the researchers who are expanding it.

ABSTRACT DEADLINE: April 13, 2009 (abstracts submitted by the deadline will be considered for short oral presentations; late abstracts will be accepted for poster presentation)

REGISTRATION COSTS: Registration includes meals (Thursday dinner through Sunday breakfast) and admission to lectures, posters and oral presentations.  Advance registration (until May 11): $500 (faculty and staff), $400 (students and postdocs).  Registration after May 11: $550 (faculty and staff), $450 (students and postdocs).


The Challenge of Systems Biology
David Hume: University of Edinburgh
A systems biology paradigm: macrophage networks in pathogen response

Modeling Genetic Effects on Biological Systems
Steve Horvath: UCLA School of Public Health
An overview of weighted gene co-expression network analysis
Dan Kliebenstein: University of California-Davis
Systems analysis of natural genomic variation in an adaptive trait;
biochemicals and plant-insect interactions
Antoni Rafalski: DuPont Experimental Station
Genome diversity and gene expression in maize
Barbara Stranger: Harvard Medical School
Population genomics of human gene expression
Lauren M. McIntyre: University of Florida - Gainesville
Deconstructing the system into testable hypotheses

Modeling Transcriptional Networks
Hamid Bolouri: California Institute of Technology
Genetic regulatory control of T-cell development: a paradigm for adult stem cell differentiation
Graziano Pesole: University of Bari
Gene complexity and alternative splicing
Timothy Ravasi: University of California-San Diego
Inferring promoters-based transcription regulatory networks in human and mouse macrophages
Rodrigo Gutierrez: Pontificia Universidad Católica de Chile
Post-transcriptional regulatory networks in the nitrogen response of Arabidopsis thaliana

Modeling Protein Interactions and Metabolic Networks
Maricel G. Kann: University of Maryland-Baltimore County
Protein Domains meet System Biology: a genome-wide approach to uncover protein domain networks
Mona Singh: Princeton University
From biological networks to cellular organization and functioning
Melissa Kemp: Georgia Tech & Emory University
Regulatory control of intracellular protein thiols
Stefan Hoops: Virginia Bioinformatics Institute
Simulation and modeling biochemical networks using platform-independent software
Chao Tang: University of California - San Francisco
Design principles of biochemical adaptation circuits

Synthetic Biology
Teresa Przytycka: NCBI, NLM, NIH
Predicting domain interaction based on protein interaction networks from multiple organisms.
Yiannis Kaznessis: University of Minnesota
Computer-aided synthetic biology: How multiscale models can rationalize the design of synthetic gene networks

Opportunities and Challenges in Multidisciplinary Training in Bioinformatics
Hamid Bolouri: California Institute of Technology
Using intensive workshops for bioinformatics training
Gary Benson: Boston University
The value of an IGERT program in training Ph.D. students in bioinformatics
Libby Shoop: Macalester College
Training undergraduate students in bioinformatics
BCB Lab group: Iowa State University
Peer to peer bioinformatics training

SITE AND DATES: The symposium will be held in the Scheman Building, Iowa State Center at Iowa State University, Ames, Iowa, U.S.A.
Registration begins at 3:00 PM and the first plenary session at 5:00 PM Thursday, June 11, 2009. The last plenary session ends at 12:00 Noon on Sunday, June 14, 2009

SYMPOSIUM COMMITTEE: Chris Tuggle, Marit Nilsen-Hamilton, Srinivas Aluru, Drena Dobbs, Karin Dorman, Vasant Honavar, and Robert Jernigan,

SPONSORED:  Graduate Program in Bioinformatics and Computational Biology, Iowa State University; Plant Sciences Institute, Iowa State University; Office of Biotechnology on its 25th Anniversary, Iowa State University; US Department of Agriculture; NSF IGERT Training Program in Computational Molecular Biology, Iowa State University; Center for Integrated Animal Genomics, Iowa State University; Baker Center for Bioinformatics and Biological Statistics, Iowa State University; Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University.

More information can be found on the symposium website:

Linda Lyngholm, Symposium Coordinator
Symposium Office
3208 Molecular Biology Building
Iowa State University
Ames, IA 50011
Tel:    (515) 294-7978
Fax:    (515) 294-2244
Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Linda Lyngholm, Symposium Coordinator
Symposium Office
3208 Molecular Biology Building
Iowa State University
Ames, IA 50011
Tel:    (515) 294-7978
Fax:    (515) 294-2244
Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Announcing a Symposium: "Systems Biology: Integrative, Comparative, and Multi-Scale Modeling" 11-15 June 2009 For information see: