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World Community Grid - You Can Help Fight Influenza! PDF Print E-mail
Written by Virginia Gonzalez   
Friday, 08 May 2009 19:03
Your donated computer time can now help find drugs to combat a future outbreak of influenza!
World Community Grid has started a new research project that will use your donated computer time to find new drugs that can stop the spread of an influenza infection in an individual. The research will specifically address the influenza strains that have become drug resistant, as well as new strains that are appearing. Your computer will help identify the chemical compounds that are the best candidates. This will accelerate the efforts to develop treatments that would be useful in managing seasonal influenza outbreaks and future influenza epidemics.

If you are currently contributing and want to check to see if you are contributing to this project, click here. If you are no longer contributing but would like to contribute to this project, please click here.

For more information about the Influenza Antiviral Drug Search project or other projects running on World Community Grid, please click here.
Last Updated on Friday, 08 May 2009 19:13
BioPortal 2.1 Release PDF Print E-mail
Written by Virginia Gonzalez   
Friday, 08 May 2009 18:53

The National Center for Biomedical Ontology announces the release of BioPortal 2.1. Highlights of this release are:

-Annotator: a service that identifies mentions of biomedical ontology concepts in text that users submit. You can use the annotator service to tag automatically any item of interest with terms from UMLS and BioPortal ontologies. The Annotator is accessible via the BioPortal user interface [1] and as a REST service [2]

-Advanced user interface for searching ontologies [3] enables users to select which ontologies or categories of ontologies to search, specify search parameters, and filter and navigate easily through the search results

-Ontology-based projects: You can now describe your ontology-based projects, indicate which BioPortal ontologies you use, and provide reviews of those ontologies in the context of your project [4]

Latest Article Alert from BMC Bioinformatics (1 May) PDF Print E-mail
Written by Sebastian Bassi   
Friday, 01 May 2009 12:32

The following new articles have just been published in BMC Bioinformatics

For articles which have only just been published, you will see a 'provisional PDF' corresponding to the accepted manuscript. A fully formatted PDF and full text (HTML) version will be made available soon.

Methodology article     
Identification of differentially expressed sub-networks based on multivariate ANOVA scoring method
Hwang T, Park T
BMC Bioinformatics 2009, 10:128 (30 April 2009)
[Abstract] [Provisional PDF]
Automated FingerPrint Background removal: FPB
Scalabrin S, Morgante M, Policriti A
BMC Bioinformatics 2009, 10:127 (30 April 2009)
[Abstract] [Provisional PDF]
Articles about Next-generation sequencing. PDF Print E-mail
Written by Administrator   
Tuesday, 05 May 2009 13:54

Next-generation sequencing technologies are revolutionising genomics and their effects are becoming increasingly widespread. Many tools and algorithms relevant to next-generation sequencing applications have been published in Bioinformatics, and so to celebrate this contribution we have gathered these together in this 'Bioinformatics for Next Generation Sequencing' virtual issue. This will be a living resource that we will continually update to include the very latest papers in this area to help researchers keep abreast of the latest developments.


Editorial -Bioinformatics for Next Generation Sequencing
Alex Bateman and John Quackenbush
Bioinformatics (2009) 25: 429 Full Text




Biopython 1.50 PDF Print E-mail
Written by Sebastian Bassi   
Monday, 20 April 2009 19:13
We are pleased to announce Biopython release 1.50, featuring some significant additions since Biopython 1.49 was released late last year.

GenomeDiagram by Leighton Pritchard has been integrated into Biopython as the Bio.Graphics.GenomeDiagram module.

A new module Bio.Motif has been added, which is intended to replace the existing Bio.AlignAce and Bio.MEME modules. Also have a look at Bio.SwissProt and Bio.ExPASy and their revised parsers.

As noted in a previous news posting, Bio.SeqIO can now read and write FASTQ and QUAL files used in second generation sequencing work. In connection with this, our SeqRecord object has a new dictionary attribute, letter_annotations, for per-letter-annotation information like sequence quality scores or secondary structure predictions. Also, the SeqRecord object can now be sliced to give a new SeqRecord covering just part of the sequence.

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